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Pharmacological pain relief

Entonox (Gas and Air)

A mixture of oxygen and nitrous oxide inhaled during contractions.

Benefits:

  • Quick acting
  • Easy to use
  • Woman remains mobile
  • Can be used at any stage of labour

Possible side effects:

  • Dizziness
  • Nausea
  • Tingling sensations

Opioid injections

Examples include diamorphine, morphine, and pethidine.

Benefits:

  • Can promote relaxation
  • May help women cope with contractions
  • Does not require specialist anaesthetic staff

Possible side effects:

  • Drowsiness
  • Nausea and vomiting
  • May temporarily affect the baby’s alertness after birth

Remifentanil PCA

Remifentanil is administered through a patient-controlled pump, allowing women to self-administer small doses as required.

Benefits:

  • Rapid onset and short duration
  • More effective than intramuscular opioids
  • Women remain in control

Considerations:

  • Requires continuous monitoring
  • May cause drowsiness and slower breathing

Epidural

An epidural is administered by an anaesthetist through a catheter inserted into the lower back.

Benefits:

  • Most effective form of labour pain relief
  • Can be topped up throughout labour
  • Can be extended if operative birth is required

Possible side effects and risks:

  • Reduced mobility
  • Additional monitoring required
  • May increase the likelihood of an assisted vaginal birth
  • Difficulty passing urine, often requiring a urinary catheter
  • Headache is an uncommon complication
  • Serious complications are very rare

Limitations:

  • Requires anaesthetic staff and can take time to establish
  • Does not work immediately; full effect may take 20-30 minutes

Find out more

Information on pain relief choices during labour
Pain relief options in labour and birth (Tommy’s)